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Orotate reductase (NADPH)
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Orotate reductase (NADPH) : ウィキペディア英語版
Orotate reductase (NADPH)

In enzymology, an orotate reductase (NADPH) () is an enzyme that catalyzes the chemical reaction
:(S)-dihydroorotate + NADP+ \rightleftharpoons orotate + NADPH + H+
Thus, the two substrates of this enzyme are (S)-dihydroorotate and NADP+, whereas its 3 products are orotate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-dihydroorotate:NADP+ oxidoreductase. Other names in common use include orotate reductase, dihydroorotate dehydrogenase, dihydro-orotic dehydrogenase, L-5,6-dihydro-orotate:NAD+ oxidoreductase, and orotate reductase (NADPH). It has one cofactor, FAD.
==References==

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